Medial septal nucleus and delayed alternation in rats
نویسندگان
چکیده
منابع مشابه
Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments.
The functional contribution of nucleus basalis magnocellularis (NBM) and the medial septal area (MSA) to memory was evaluated in two different spatial discriminations. Preoperatively, rats were trained to a criterion level of performance in a simultaneous left/right discrimination on the stem of a T-maze (a trial-independent memory) and a discrete-trial, rewarded alternation discrimination on t...
متن کاملDelayed Alternation 1 Running head: DELAYED ALTERNATION Prefrontal contributions to delayed spatial and object alternation: A PET study
Delayed alternation tasks are frequently employed as probes of frontal lobe functioning. In order to clarify the neural substrates of delayed alternation performance in humans, we measured regional cerebral blood flow with H20 PET in healthy subjects as they performed delayed spatial and object alternation. Consistent with the monkey lesion literature, increased dorsolateral prefrontal activity...
متن کاملRossi Et Al. Delayed Alternation Prefrontal Cortical Mechanisms Underlying Delayed Alternation in Mice Abbreviated Title: Delayed Alternation 2
34 The prefrontal cortex (PFC) has been implicated in the maintenance of task-relevant information 35 during goal-directed behavior. Using a combination of lesions, local inactivation, and 36 optogenetics, we investigated the functional role of the medial prefrontal cortex (mPFC) in mice 37 using a novel operant delayed alternation task. Task difficulty was manipulated by changing the 38 durati...
متن کاملThe presence of home-cage stimuli attenuates spontaneous-alternation deficits in rats with septal lesions
The present experiment examined the effects of the olfactory context on spontaneousalternation performance of young adult, female rats following septal lesions. Separate groups of rats were given either septal lesions (n=24) or control surgery (n=24), and then tested on the 8th postoperative day for spontaneous alternation across three trials. Half of the rats in each surgical group were tested...
متن کاملCatecholamines and DOPAC in cortical and neostriatal regions during rats' learning of delayed alternation.
Dopamine, norepinephrine and DOPAC were measured in two cortical areas (the medial prefrontal and the posterolateral, Te2) and in the anterior and posterior neostriatum in rats which were exposed to three different experiences for three different lengths of time. One group learned delayed alternation and the two others served as controls. Throughout the training period all animals were housed i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physiological Psychology
سال: 1980
ISSN: 0090-5046
DOI: 10.3758/bf03326477